What are the biggest challenges you’ve faced with Azure PaaS scaling and multi-region architecture,

What are the biggest challenges you’ve faced with Azure PaaS scaling and multi-region architecture, and how did you solve them?

I’m exploring Azure PaaS Services for a cloud-native application and trying to understand potential pitfalls early.

Issues with auto-scaling reliability?
Multi-region latency or failover concerns?
Data consistency strategies (eventual vs strong consistency)?

Looking for real-world solutions and recommendations.