Switzerland localization is expected to be release in July. I probably would wait and upgrade to that release. Don't forget that you need upgrade toolkit and that tool will be only released in July or August.
NAV 5.0 has some nice new features and its better optimized for SQL. If you have a large database you will notice performance improvements.
SQL Server 2005 it's a better version that SQL 2000
It depends if the changes in NAV 5.0 will be used. Of course, NAV 5.0 is more optimized for SQL, it means you will gain some performance by doing upgrade to NAV 5.0 instead 4.00SP3.
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NAV 5.0 has some nice new features and its better optimized for SQL. If you have a large database you will notice performance improvements.
SQL Server 2005 it's a better version that SQL 2000
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